Other Names Macrophage metalloelastase [Precursor], EC 3.4.24.65, HME, Matrix metalloproteinase-12, MMP-12, Macrophage elastase, ME, MMP12, HME
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized peptide derived from human MMP12.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/Sensitivity MMP12 (Cleaved-Glu106) antibody detects endogenous levels of fragment of activated MMP12 resulting from cleavage adjacent to Glu106.
ReferencesShapiro S.D., J. Biol. Chem. 268:23824-23829(1993).
Gronski T.J. Jr., J. Biol. Chem. 272:12189-12194(1997).
Lang R., J. Mol. Biol. 312:731-742(2001).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells