All Names
AlternameInsulin receptor substrate 1, IRS-1, IRS1
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of Ser307.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide.
Specificty Sensitivity
Specificity/SensitivityIRS-1 (Phospho-Ser307) Antibody detects endogenous levels of IRS-1 only when phosphorylated at Ser307.
ReferencesWhite M.F., Kahn C.R.Diabetes 42:1041-1054 1993
Gertler F.B., Carlier M.-F.J. Cell Biol. 144:1245-1258(1999)
Sugano S.Nat. Genet. 36:40-45(2004)
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells