All Names
AlternameSpleen tyrosine kinase, PROTEIN-TYROSINE KINASE SYK
All SitesHuman: Tyr348; Mouse: Tyr342; Rat: Tyr342
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human SYK around the phosphorylation site of tyrosine 348 (E-V-YP-E-S).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivitySYK (phospho-Tyr348) antibody detects endogenous levels of SYK only when phosphorylated at tyrosine 348.
ReferencesJurgen Schymeinsky, Blood, Dec 2006; 108: 3919 - 3927.
Clément Couture, J. Biol. Chem., Sep 1996; 271: 24294.
Kiyonao Sada, J. Biochem. (Tokyo), Aug 2001; 130: 177 - 186.
Hiroshi Harayama, J Androl, Nov 2005; 26: 732 - 740.
Vincenzo Di Bartolo, J. Biol. Chem., Mar 1999; 274: 6285.