All Names
AlternamePTK2B protein tyrosine kinase 2 beta isoform a, PTK2B protein tyrosine kinase 2 beta isoform b, calcium-dependent tyrosine kinase, cell adhesion kinase beta, focal adhesion kinase 2, proline-rich tyrosine kinase 2 protein kinase B, related adhesion focal tyrosine kinase
All SitesHuman: Tyr580; Mouse: Tyr580; Rat: Tyr580
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human PYK2 around the phosphorylation site of tyrosine 580 (D-Y-YP-K-A).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityPYK2 (phospho-Tyr580) antibody detects endogenous levels of PYK2 only when phosphorylated at tyrosine 580.
ReferencesYoshiko Banno, J. Biol. Chem., Apr 2005; 280: 16319 - 16324.
Robin R. Hodges, Invest. Ophthalmol. Vis. Sci., Aug 2006; 47: 3352 - 3359.
Sarah J. McLeod, J. Biol. Chem., Mar 2004; 279: 12009 - 12019.
Chong-Shan Shi, J. Biol. Chem., Aug 2000; 275: 24470