Other Names 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2; EC 3.1.4.11; phospholipase C-gamma-2; PLC-gamma2; PLC-IV
All Sites Human: Tyr753; Mouse: Tyr753; Rat: Tyr753
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human PLCG2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity PLCG2 (Phospho-Tyr753) antibody detects endogenous levels of PLCG2 only when phosphorylated at tyrosine 753.
ReferencesOhta S., FEBS Lett. 242-31-35(1988).
Kemmer D., BMC Genomics 7:48-48(2006).
Martin J., Nature 432:988-994(2004).