All Names
Altername1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3,EC 3.1.4.11, Phosphoinositide phospholipase C,Phospholipase C-beta-3,PLC-beta-3,PLCB3
All SitesHuman: Ser1105; Mouse: Ser1105; Rat: Ser1105
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human PLC-β around the phosphorylation site of serine 1105 (N-N-SP-I-S).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityPLC-β (phospho-Ser1105) antibody detects endogenous levels of PLC-β only when phosphorylated at serine 1105.
ReferencesChunzhi Xia, J. Biol. Chem., Jun 2001; 276: 19770 - 19777.
Helena Frecker, Am J Physiol Renal Physiol, Nov 2005; 289: F1078 - F1087.
Clive P. Morgan, J. Biol. Chem., Nov 2004; 279: 47159 - 47171.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells