All Names
AlternameEC 3.1.1.79, Hormone sensitive lipase, LIPE, LIPS
All SitesHuman: Ser855; Mouse: Ser559; Rat: Ser865
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human HSL around the phosphorylation site of serine 855/554 (S-V-SP-E-A).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityHSL (Phospho-Ser855/554) antibody detects endogenous levels of HSL only when phosphorylated at serine 855/554.
ReferencesMatthew J. Watt, Am J Physiol Endocrinol Metab, Mar 2006; 290: E500 - E508.
Maya S. Gowri, Am J Physiol Endocrinol Metab, Sep 2000; 279: E593 - E600.
Matthew J. Watt, Am J Physiol Endocrinol Metab, Jul 2004; 287: E120 - E127.
Shu Pei Wang, Endocrinology, Dec 2004; 145: 5688 - 5693.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells