All Names
AlternameApoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Caspase 8 around the phosphorylation site of serine 347 (C-P-S-L-A).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityCaspase 8 (Ab-347) antibody detects endogenous levels of total Caspase 8 protein.
ReferencesDaniel R. Beisner, J. Immunol., Sep 2005; 175: 3469 - 3473.
Peter J. Wild, Mol. Cancer Ther., Apr 2005; 4: 516 - 528.
A.V. TIMOFEEVA, Ann. N.Y. Acad. Sci., Dec 2006; 1091: 319 - 335.
Leon Tourian, J. Cell Sci., Dec 2004; 117: 6459 - 6471.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells