All Names
AlternameApoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
All SitesHuman: Ser21; Mouse: Ser21; Rat: Ser21
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human C/EBP-α around the phosphorylation site of serine 21 (L-Q-SP-P-P).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityC/EBP-α (phospho-Ser21) antibody detects endogenous levels of C/EBP-α only when phosphorylated at serine 21.
ReferencesTakashi Akasaka, Blood, Apr 2007; 109: 3451 - 3461.
Carolina Gillio-Meina, Biol Reprod, May 2005; 72: 1194 - 1204.
Raphaël Métivier, Mol. Endocrinol., Nov 2001; 15: 1953.
Neoncheol Jung, Eur. J. Biochem., Oct 2000; 267: 6180.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells