All Names
AlternameAGMX1, ATK, Agammaglobulinaemia tyrosine kinase, B cell progenitor kinase, BPK, Bruton's tyrosine kinase, EC 2.7.10.2, Kinase EMB, kinase Btk
All SitesHuman: Tyr551; Mouse: Tyr551; Rat:Tyr552
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human BTK around the phosphorylation site of tyrosine 551 (D-E-YP-T-S).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityBTK (phospho-Tyr551) antibody detects endogenous levels of BTK only when phosphorylated at tyrosine 551.
ReferencesSulekha Verma, J. Biol. Chem., Feb 2001; 276: 4671 - 4676.
Yan M. Li, Cancer Res., Nov 2003; 63: 7630 - 7633.
Malti Nikrad, Mol. Cancer Ther., Mar 2005; 4: 443 - 449.
Feng Dong, Infect. Immun., Mar 2005; 73: 1861 - 1864.