All Names
AlternameEC 1.14.16.2, TH isoform 3, TH isoform a, TH-4, TY3H, TYH, Tyrosine 3-hydroxylase, Tyrosine 4-monooxygenase, tyrosine hydroxylase
All SitesHuman: Ser62; Mouse: Ser31; Rat: Ser31
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 31 (V-T-SP-P-R).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityTyrosine Hydroxylase (phospho-Ser31) antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 31.
ReferencesJahan Ara, PNAS, Jun 1998; 95: 7659.
E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107.
P. William Conrad, J. Biol. Chem., Nov 1999; 274: 33709.
Y. Katayama, J Appl Physiol, Nov 1994; 77: 2086.