All Names
AlternameEC 2.7.10.1, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK, TRK1 transforming tyrosine kinase protein, TRKA, Trk-A, kinase TrkA, p140-TrkA
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Trk A around the phosphorylation site of tyrosine 791 (P-V-YP-L-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityTrk A (phospho-Tyr791) antibody detects endogenous levels of Trk A only when phosphorylated at tyrosine 791.
ReferencesTina Garofalo, J. Biol. Chem., Dec 1998; 273: 35153.
Jan Grimm, J. Cell Biol., Jul 2001; 154: 345.
Jose L. Tomsig, J Androl, May 2006; 27: 348 - 357.
VI Shifrin and BG Neel J. Biol. Chem., Dec 1993; 268: 25376 - 25384.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells