All Names
AlternameHS90B, HSP 84, HSP90-beta, HSP90AB1, HSPC2, HSPCB, Heat shock protein HSP 90-beta
All SitesHuman: Ser254; Mouse: Ser254; Rat: Ser254
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human HSP90B around the phosphorylation site of serine 254 (V-G-SP-D-E).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityHSP90B (phospho-Ser254) antibody detects endogenous levels of HSP90B only when phosphorylated at serine 254.
ReferencesLothar Goretzki, AACR Meeting Abstracts, Apr 2006; 2006: 468.
Jean-François Louvion, Mol. Biol. Cell, Nov 1998; 9: 3071.
Angelika Lueking, Mol. Cell. Proteomics, Dec 2003; 2: 1342.
Jason Fontana Circ, Res., May 2002; 90: 866.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells