All Names
AlternameCREB-1, CREB1, cAMP-response element binding protein
All SitesHuman: Ser142; Mouse: Ser142; Rat: Ser142
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of serine 142 (D-L-SP-S-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityCREB (phospho-Ser142) antibody detects endogenous levels of CREB only when phosphorylated at serine 142.
ReferencesAnjali Rajadhyaksha, J. Neurosci., Aug 1999; 19: 6348.
Brian F. Clem, Endocrinology, Mar 2005; 146: 1348 - 1356.
Boyoung Lee, J. Neurosci., Feb 2005; 25: 1137 - 1148.
Lance Zirpel, J. Neurosci., Aug 2000; 20: 6267.