Other Names CAMK2A, CaM-kinase II alpha chain, CaMK-II alpha subunit, CaMKII-alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, EC 2.7.11.17, KCC2A, kinase CaMK2-alpha
All Sites Human: Thr305; Mouse: Thr305; Rat: Thr305
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human CaMKII around the phosphorylation site of threonine 305 (I-L-TP-T-M).
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity CaMKII (Phospho-Thr305) antibody detects endogenous levels of CaMKII only when phosphorylated at threonine 305.
ReferencesCarl W. Tong, J. Physiol., Aug 2004; 558: 927 - 941.
Pierre R, J. Biol. Chem., Sep 1997; 272: 24133.
Daliang Wang, PNAS, Jun 1998; 95: 7133.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells