BackgroundThis gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Information
Clone Number3F10
SpeciesMouse IgG1
Entrez Gene8842
Recommended DilutionsIHC:1/200 - 1/1000, FC:1/200 - 1/400, ELISA: Propose dilution 1/10000.
Molecular Weight133kDa
All Names
AlternameRP41; AC133; CD133; MCDR2; STGD4; CORD12
ImmunogenSynthesized peptide of human CD133 (AA: 20-36, GGQPSSTDAPK AWNYELc)
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells