BackgroundThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Product Information
Clone Number3A9
SpeciesMouse IgG1
Entrez Gene2022
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000, FC: 1/200 - 1/400,ELISA: Propose dilution 1/10000.
Molecular Weight71kDa
FormulationAscitic fluid containing 0.03% sodium azide.
All Names
AlternameENG; END; ORW; HHT1; ORW1; CD105; FLJ41744
ImmunogenPurified recombinant fragment of human CD105 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.