BackgroundThe protein encoded by this gene catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Product Information
Clone Number5D3
SpeciesMouse IgG1
Entrez Gene4524
Recommended DilutionsWB: 1/500 - 1/2000, IHC:1/200-1/1000, ELISA: Propose dilution 1/10000.
Molecular Weight75kDa
ImmunogenPurified recombinant fragment of human MTHFR expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells