BackgroundThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Product Information
Clone Number5A6
SpeciesMouse IgG1
Entrez Gene983
Recommended DilutionsWB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Molecular Weight34kDa
All Names
AlternameCDC2; CDC28A; P34CDC2; MGC111195; DKFZp686L20222; CDK1
ImmunogenPurified recombinant fragment of human CDK1 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells