BackgroundThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
Product Information
Clone Number4F12
SpeciesMouse IgG1
Entrez Gene1386
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000.
Molecular Weight55kDa
All Names
AlternameHB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2
ImmunogenPurified recombinant fragment of human ATF2 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells