BackgroundProtein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al. 2002 (PubMed 11724789). Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
Product Information
Clone Number3H2
SpeciesMouse IgG1
Entrez Gene10498
Recommended DilutionsWB: 1/500 - 1/2000, IHC:1/200-1/1000, IF: 1/200-1/1000, FC:1/200-1/400,
ELISA: Propose dilution 1/10000.
Molecular Weight65kDa
All Names
AlternamePRMT4; CARM1
ImmunogenPurified recombinant fragment of human CARM1 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells