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BLK Antibody
Datasheet
Catalog Number:
E10-30135Amount:
100μg/100μlBackground:
Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .Clone Number:
1E6Species:
Mouse IgG1Altername:
MODY11; MGC10442; BLKEntrez Gene:
640Immunogen:
Purified recombinant fragment of human BLK expressed in E. Coli.Storage/Stability:
Store at 4℃, for long term storage, store at -20℃.Form of Antibody:
Ascitic fluid containing 0.03% sodium azide.Reactivity:
HumanRecommended Dilutions:
WB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
- Figure 1: Western blot analysis using BLK mAb against HEK293 (1) and BLK-hIgGFc transfected HEK293 (2) cell lysate.
- Figure 2: Immunofluorescence analysis of Hela cells using BLK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
- Figure 3: Flow cytometric analysis of HL-60 cells using BLK mouse mAb (green) and negative control (purple).
Price:
225$Molecular Weight:
58kDaApplications:
WB, IF, FC, ELISA. Not yet tested in other applications.Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
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Catalog Number
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