World supplier of antibodies, antigens and kits since 2007
Primary Antibodies
CDH1 Antibody
Human; Mouse; Monkey
WB, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundE-Cadherin is a 120 kDa transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells. There, it interacts with the cytoskeleton through the associated cytoplasmic catenin proteins. In addition to being a calcium-dependent adhesion molecule, E-Cadherin is also a critical regulator of epithelial junction formation. Its association with catenins is necessary for cell-cell adhesion. These E-cadherin/catenin complexes associate with corical actin bundles at both the zonula adherens and the lateral adhesion plaques. Tyrosine phosphorylation can disrupt these complexes, leading to changes in cell adhesion properties. E-Cadherin expression is often down-regulated in highly invasive, poorly differentiated carcinomas. Increased expression of E-Cadherin in these cells reduces invasiveness. Thus, loss of expression or function of E-Cadherin appears to be an important step in tumorigenic progression.Tissue specificity: Non-neural epithelial tissues.
Product Information
Clone Number7A2
SpeciesMouse IgG1
Entrez Gene999
Recommended DilutionsWB: 1/500 - 1/2000,
ELISA: Propose dilution 1/10000.
ELISA: Propose dilution 1/10000.
Molecular Weight135kDa
All Names
AlternameUVO; CDHE; ECAD; LCAM; Arc-1; CD324; CDH1
ImmunogenPurified recombinant fragment of human CDH1 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
blot analysis using CDH1 mouse mAb against LNCAP (1)，A431 (2), DU145 T47D(6) cell lysate.
Conjugated Antibody
This product is also available conjugated. Format: E10-30127-Conjugate. Price: $485 / Size: 100μl.
E10-30127-FITC$485 / 100μlE10-30127-Biotin$485 / 100μlE10-30127-HRP$485 / 100μlE10-30127-AP$485 / 100μlE10-30127-AF350$485 / 100μlE10-30127-AF405M$485 / 100μlE10-30127-AF488$485 / 100μlE10-30127-AF514$485 / 100μlE10-30127-AF532$485 / 100μlE10-30127-AF555$485 / 100μlE10-30127-AF568$485 / 100μlE10-30127-AF405S$485 / 100μlE10-30127-AF405L$485 / 100μlE10-30127-AF546$485 / 100μlE10-30127-AF594$485 / 100μlE10-30127-AF610$485 / 100μlE10-30127-AF635$485 / 100μlE10-30127-AF647$485 / 100μlE10-30127-AF680$485 / 100μlE10-30127-AF700$485 / 100μlE10-30127-AF750$485 / 100μlE10-30127-AF790$485 / 100μlE10-30127-APC$485 / 100μlE10-30127-PE$485 / 100μlE10-30127-Cy3$485 / 100μlE10-30127-Cy5$485 / 100μlE10-30127-Cy5.5$485 / 100μlE10-30127-Cy7$485 / 100μlE10-30127-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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