BackgroundThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Product Information
Clone Number5G2
SpeciesMouse IgG1
Entrez Gene4982
Recommended DilutionsWB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400,
ELISA: Propose dilution 1/10000.
Molecular Weight60kDa
All Names
AlternameOPG; TR1; OCIF; MGC29565; TNFRSF11B
ImmunogenPurified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells