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Primary Antibodies
STAT3 Antibody
Human; Mouse; Monkey
WB, IHC, IF, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundThe Stat3 transcription factor is an important signaling molecule for many cytokines and growth-factor receptors and is required for murine fetal development . Stat3 is constitutively activated in a number of human tumors and possesses oncogenic potential and anti-apoptotic activities. Stat3 is activated by phosphorylation at Tyr705, which induces dimerization, nuclear translocation and DNA binding. Transcriptional activation seems to be regulated by phosphorylation at Ser727 through the MAPK or mTOR pathways. Stat3 isoform expression appears to reflect biological function as the relative expression levels of Stat3α (86 kDa) and Stat3β (79 kDa) depend on cell type, ligand exposure or cell maturation stage. It is notable that Stat3β lacks the serine phosphorylation site within the carboxy-terminal transcriptional activation domain.Tissue specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Product Information
Clone Number3B5
SpeciesMouse IgG1
Entrez Gene6774
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF: 1/200 - 1/1000,
ELISA: Propose dilution 1/10000.
ELISA: Propose dilution 1/10000.
Molecular Weight88kDa
All Names
AlternameAPRF; HIES; FLJ20882; MGC16063; STAT3
ImmunogenPurified recombinant fragment of human STAT3 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
analysis of paraffin-embedded mammary cancer tissues tissues (right) using STAT3 mouse mAb with DAB staining.
analysis of Hela cells using STAT3 mouse mAb (green). DNA dye. Red: Actin filaments have been labeled with Alexa
Conjugated Antibody
This product is also available conjugated. Format: E10-30122-Conjugate. Price: $485 / Size: 100μl.
E10-30122-FITC$485 / 100μlE10-30122-Biotin$485 / 100μlE10-30122-HRP$485 / 100μlE10-30122-AP$485 / 100μlE10-30122-AF350$485 / 100μlE10-30122-AF405M$485 / 100μlE10-30122-AF488$485 / 100μlE10-30122-AF514$485 / 100μlE10-30122-AF532$485 / 100μlE10-30122-AF555$485 / 100μlE10-30122-AF568$485 / 100μlE10-30122-AF405S$485 / 100μlE10-30122-AF405L$485 / 100μlE10-30122-AF546$485 / 100μlE10-30122-AF594$485 / 100μlE10-30122-AF610$485 / 100μlE10-30122-AF635$485 / 100μlE10-30122-AF647$485 / 100μlE10-30122-AF680$485 / 100μlE10-30122-AF700$485 / 100μlE10-30122-AF750$485 / 100μlE10-30122-AF790$485 / 100μlE10-30122-APC$485 / 100μlE10-30122-PE$485 / 100μlE10-30122-Cy3$485 / 100μlE10-30122-Cy5$485 / 100μlE10-30122-Cy5.5$485 / 100μlE10-30122-Cy7$485 / 100μlE10-30122-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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