BackgroundThis gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.
Product Information
Clone Number5A8
SpeciesMouse IgG1
Entrez Gene4143
Recommended DilutionsWB: 1/500 - 1/2000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.
Molecular Weight54kDa
All Names
AlternameMAT; SAMS; MATA1; SAMS1; MAT1A
ImmunogenPurified recombinant fragment of human MATN1 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells