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Primary Antibodies
CD276 Antibody
Human
WB, IF, FC, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundCostimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Product Information
Clone Number6A1
SpeciesMouse IgG1
Entrez Gene80381
Recommended DilutionsWB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
Molecular Weight57kDa
All Names
AlternameB7H3; B7-H3; 4Ig-B7-H3; CD276
ImmunogenPurified recombinant fragment of human CD276 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1: Western blot analysis using CD276 mAb against HEK293 (1) and CD276-hIgGFc transfected Figure 3: Flow cytometric HEK293 (2) cell lysate. negative control (purple).
analysis of paraffin-embedded cervical cancer tissues tissues (right) using CD276 mouse mAb with DAB staining.
analysis of PC-3 cells using CD276 mouse mAb (green) and
Conjugated Antibody
This product is also available conjugated. Format: E10-30103-Conjugate. Price: $485 / Size: 100μl.
E10-30103-FITC$485 / 100μlE10-30103-Biotin$485 / 100μlE10-30103-HRP$485 / 100μlE10-30103-AP$485 / 100μlE10-30103-AF350$485 / 100μlE10-30103-AF405M$485 / 100μlE10-30103-AF488$485 / 100μlE10-30103-AF514$485 / 100μlE10-30103-AF532$485 / 100μlE10-30103-AF555$485 / 100μlE10-30103-AF568$485 / 100μlE10-30103-AF405S$485 / 100μlE10-30103-AF405L$485 / 100μlE10-30103-AF546$485 / 100μlE10-30103-AF594$485 / 100μlE10-30103-AF610$485 / 100μlE10-30103-AF635$485 / 100μlE10-30103-AF647$485 / 100μlE10-30103-AF680$485 / 100μlE10-30103-AF700$485 / 100μlE10-30103-AF750$485 / 100μlE10-30103-AF790$485 / 100μlE10-30103-APC$485 / 100μlE10-30103-PE$485 / 100μlE10-30103-Cy3$485 / 100μlE10-30103-Cy5$485 / 100μlE10-30103-Cy5.5$485 / 100μlE10-30103-Cy7$485 / 100μlE10-30103-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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