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Primary Antibodies
ALDH1A1 Antibody
Human
WB, IHC, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundALDH1A1 is an aldehyde dehydrogenase able to oxidize a wide variety of aliphatic aldehydes (retinaldehyde, acetaldehyde, etc.) to the corresponding carboxylic acids (retinoic acid, acetic acid, etc.). ALDH1A1 (also known as RALDH1, ALDH1, or AHD2) is highly expressed in the dorsal retina, ventral midbrain (dopaminergic neurons), and hematopoietic stem cells. ALDH1A1 is involved in retinoic acid (RA) synthesis during vertebrate embryogenesis. ALDH1A1 is first detected at E9.0-E10.5 in cranial tissues (ventral mesencephalon, dorsal retina, thymic primordia, optic vesicles) and in the mesonephros. ALDH1A1 is also of interest in Parkinson's Disease (PD) being expressed in the the A9 dopaminergic (DA) neuronal group projecting to the dorsal striatum; this is the most vulnerable site in PD (Chung et al, 2005). ALDH1A1 protein is a known mesencephalic dopaminergic marker. ALDH1A1 is a cytosolic enzyme that preferentially oxidizes retinaldehyde to retinoic acid .ALDH1A1 is expressed in the epithelium of many organs, including brain, liver, testis, eye lens and cornea .
Product Information
Clone Number5A11
SpeciesMouse IgG1
Entrez Gene216
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ELISA: Propose dilution 1/10000.
Molecular Weight55kDa
ImmunogenPurified recombinant fragment of human ALDH1A1 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1: Western blot analysis using ALDH1A1 mouse mAb against Raji (1), Jurkat (2), THP-1 (3) and K562 (4) cell lysate.
2: Immunohistochemical analysis of paraffin-embedded tissues (left) and lung cancer (right) using ALDH1A1 mAb with DAB staining.
Conjugated Antibody
This product is also available conjugated. Format: E10-30102-Conjugate. Price: $485 / Size: 100μl.
E10-30102-FITC$485 / 100μlE10-30102-Biotin$485 / 100μlE10-30102-HRP$485 / 100μlE10-30102-AP$485 / 100μlE10-30102-AF350$485 / 100μlE10-30102-AF405M$485 / 100μlE10-30102-AF488$485 / 100μlE10-30102-AF514$485 / 100μlE10-30102-AF532$485 / 100μlE10-30102-AF555$485 / 100μlE10-30102-AF568$485 / 100μlE10-30102-AF405S$485 / 100μlE10-30102-AF405L$485 / 100μlE10-30102-AF546$485 / 100μlE10-30102-AF594$485 / 100μlE10-30102-AF610$485 / 100μlE10-30102-AF635$485 / 100μlE10-30102-AF647$485 / 100μlE10-30102-AF680$485 / 100μlE10-30102-AF700$485 / 100μlE10-30102-AF750$485 / 100μlE10-30102-AF790$485 / 100μlE10-30102-APC$485 / 100μlE10-30102-PE$485 / 100μlE10-30102-Cy3$485 / 100μlE10-30102-Cy5$485 / 100μlE10-30102-Cy5.5$485 / 100μlE10-30102-Cy7$485 / 100μlE10-30102-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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