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Primary Antibodies

RICTOR Antibody

E10-30093Cite ID: EN0013767DatasheetCOAMSDS
Human; Monkey; Mouse
WB, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

BackgroundCell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals . mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, Sin1 and rictor . The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro . This phosphorylation is essential for full Akt/PKB activation. Furthermore, an siRNA knockdown of rictor inhibits Ser473 phosphorylation in 3T3-L1 adipocytes . This complex has also been shown to phosphorylate the rapamycin-resistant mutants of S6K1, another effector of mTOR .

Product Information

Clone Number4H5
SpeciesMouse IgG1
Entrez Gene253260
Recommended DilutionsWB: 1/500 - 1/2000,
ELISA: Propose dilution 1/10000.
Molecular Weight192kDa

All Names

AlternamePIA; mAVO3; KIAA1999; MGC39830; DKFZp686B11164; RICTOR
ImmunogenPurified recombinant fragment of human RICTOR expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.

Form Or Antibody

Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
1: Western blot analysis using RICTOR mouse mAb against Hela (1), MOLT4 (3), and HepG2 (4) cell lysate.
1: Western blot analysis using RICTOR mouse mAb against Hela (1), MOLT4 (3), and HepG2 (4) cell lysate.

Conjugated Antibody

This product is also available conjugated. Format: E10-30093-Conjugate. Price: $485 / Size: 100μl.

E10-30093-FITC$485 / 100μlE10-30093-Biotin$485 / 100μlE10-30093-HRP$485 / 100μlE10-30093-AP$485 / 100μlE10-30093-AF350$485 / 100μlE10-30093-AF405M$485 / 100μlE10-30093-AF488$485 / 100μlE10-30093-AF514$485 / 100μlE10-30093-AF532$485 / 100μlE10-30093-AF555$485 / 100μlE10-30093-AF568$485 / 100μlE10-30093-AF405S$485 / 100μlE10-30093-AF405L$485 / 100μlE10-30093-AF546$485 / 100μlE10-30093-AF594$485 / 100μlE10-30093-AF610$485 / 100μlE10-30093-AF635$485 / 100μlE10-30093-AF647$485 / 100μlE10-30093-AF680$485 / 100μlE10-30093-AF700$485 / 100μlE10-30093-AF750$485 / 100μlE10-30093-AF790$485 / 100μlE10-30093-APC$485 / 100μlE10-30093-PE$485 / 100μlE10-30093-Cy3$485 / 100μlE10-30093-Cy5$485 / 100μlE10-30093-Cy5.5$485 / 100μlE10-30093-Cy7$485 / 100μlE10-30093-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.