BackgroundInhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
Product Information
Clone Number7B4
SpeciesMouse IgG1
Entrez Gene4793
Recommended DilutionsWB: 1/500 - 1/2000,
ELISA: Propose dilution 1/10000.
Molecular Weight45kDa
All Names
AlternameIKBB; TRIP9; NFKBIB
ImmunogenPurified recombinant fragment of human NFKBIB expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells