BackgroundFOXP3 (a 431 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
Product Information
Clone Number4C7
SpeciesMouse IgG1
Entrez Gene50943
Recommended DilutionsWB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Molecular Weight47.2kDa
All Names
AlternameJM2; AIID; IPEX; PIDX; XPID; DIETER; MGC141961; MGC141963; FOXP3
ImmunogenPurified recombinant fragment of human FOXP3 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells