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Primary Antibodies

IHOG Antibody

E10-30057Cite ID: EN0013731DatasheetCOAMSDS
WB, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

BackgroundThe ihog gene (interference hedgehog), identified by RNA interference in Drosophila cultured cells, encodes a type 1 membrane protein shown here to bind and to mediate response to the active Hedgehog (Hh) protein signal. ihog mutations produce defects characteristic of Hh signaling loss in embryos and imaginal discs, and epistasis analysis places ihog action at or upstream of the negatively acting receptor component, Patched (Ptc). The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc. Other members of the Ihog family, including Drosophila Boi and mammalian CDO and BOC, also interact with Hh ligands via a specific FNIII domain, thus identifying an evolutionarily conserved family of membrane proteins that function in Hh signal response.

Product Information

Clone Number3G8
SpeciesMouse IgG1
Entrez Gene33972
Recommended DilutionsWB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Molecular Weight98kDa

All Names

AlternameCG9211; CT26314; Dmel\CG9211; ihog; Ihog
ImmunogenPurified recombinant fragment of human IHOG expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.

Form Or Antibody

Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Western blot analysis using IHOG mAb against HEK293 cell lysate.
Western blot analysis using IHOG mAb against HEK293 cell lysate.

Conjugated Antibody

This product is also available conjugated. Format: E10-30057-Conjugate. Price: $485 / Size: 100μl.

E10-30057-FITC$485 / 100μlE10-30057-Biotin$485 / 100μlE10-30057-HRP$485 / 100μlE10-30057-AP$485 / 100μlE10-30057-AF350$485 / 100μlE10-30057-AF405M$485 / 100μlE10-30057-AF488$485 / 100μlE10-30057-AF514$485 / 100μlE10-30057-AF532$485 / 100μlE10-30057-AF555$485 / 100μlE10-30057-AF568$485 / 100μlE10-30057-AF405S$485 / 100μlE10-30057-AF405L$485 / 100μlE10-30057-AF546$485 / 100μlE10-30057-AF594$485 / 100μlE10-30057-AF610$485 / 100μlE10-30057-AF635$485 / 100μlE10-30057-AF647$485 / 100μlE10-30057-AF680$485 / 100μlE10-30057-AF700$485 / 100μlE10-30057-AF750$485 / 100μlE10-30057-AF790$485 / 100μlE10-30057-APC$485 / 100μlE10-30057-PE$485 / 100μlE10-30057-Cy3$485 / 100μlE10-30057-Cy5$485 / 100μlE10-30057-Cy5.5$485 / 100μlE10-30057-Cy7$485 / 100μlE10-30057-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.