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Primary Antibodies
SHH Antibody
Human
WB, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundThis gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities.
Product Information
Clone Number8G3
SpeciesMouse IgG1
Entrez Gene6469
Recommended DilutionsWB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Molecular Weight49.6kDa
All Names
AlternameTPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; SHH
ImmunogenPurified recombinant fragment of human SHH expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
analysis using SHH mAb against SHH-hIgGFc transfected
Conjugated Antibody
This product is also available conjugated. Format: E10-30056-Conjugate. Price: $485 / Size: 100μl.
E10-30056-FITC$485 / 100μlE10-30056-Biotin$485 / 100μlE10-30056-HRP$485 / 100μlE10-30056-AP$485 / 100μlE10-30056-AF350$485 / 100μlE10-30056-AF405M$485 / 100μlE10-30056-AF488$485 / 100μlE10-30056-AF514$485 / 100μlE10-30056-AF532$485 / 100μlE10-30056-AF555$485 / 100μlE10-30056-AF568$485 / 100μlE10-30056-AF405S$485 / 100μlE10-30056-AF405L$485 / 100μlE10-30056-AF546$485 / 100μlE10-30056-AF594$485 / 100μlE10-30056-AF610$485 / 100μlE10-30056-AF635$485 / 100μlE10-30056-AF647$485 / 100μlE10-30056-AF680$485 / 100μlE10-30056-AF700$485 / 100μlE10-30056-AF750$485 / 100μlE10-30056-AF790$485 / 100μlE10-30056-APC$485 / 100μlE10-30056-PE$485 / 100μlE10-30056-Cy3$485 / 100μlE10-30056-Cy5$485 / 100μlE10-30056-Cy5.5$485 / 100μlE10-30056-Cy7$485 / 100μlE10-30056-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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