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Primary Antibodies
FAK Antibody
Human
WB, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. Tissue specificity: Expressed in all organs tested, in lymphoid cell lines, but most abundantly in brain.RD: Focal adhesion kinase 1 (FAK) is a ubiquitously expressed non-receptor protein tyrosine kinase that is concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This cellular localization is directed by a “Focal Adhesion Targeting” (FAT) sequence, a 125 amino acid sequence at the C-terminus. FAK plays an important role in migration, cell spreading, differentiation, cytoskeleton protein phosphorylation, apoptosis and acceleration of the G1 to S phase transition of the cell cycle. It associates with several different signaling proteins such as Src-family PTKs, p130Cas, Shc, Grb2, PI 3-kinase, and paxillin.
Product Information
Clone Number10H7A6
SpeciesMouse IgG1
Entrez Gene5747
Recommended DilutionsWB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.
Molecular Weight119kDa
All Names
AlternameFAK; FADK; FAK1; FRNK; pp125FAK; PTK2
ImmunogenPurified recombinant fragment of human FAK expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
using FAK mAb against FAK-hIgGFc transfected
Conjugated Antibody
This product is also available conjugated. Format: E10-30052-Conjugate. Price: $485 / Size: 100μl.
E10-30052-FITC$485 / 100μlE10-30052-Biotin$485 / 100μlE10-30052-HRP$485 / 100μlE10-30052-AP$485 / 100μlE10-30052-AF350$485 / 100μlE10-30052-AF405M$485 / 100μlE10-30052-AF488$485 / 100μlE10-30052-AF514$485 / 100μlE10-30052-AF532$485 / 100μlE10-30052-AF555$485 / 100μlE10-30052-AF568$485 / 100μlE10-30052-AF405S$485 / 100μlE10-30052-AF405L$485 / 100μlE10-30052-AF546$485 / 100μlE10-30052-AF594$485 / 100μlE10-30052-AF610$485 / 100μlE10-30052-AF635$485 / 100μlE10-30052-AF647$485 / 100μlE10-30052-AF680$485 / 100μlE10-30052-AF700$485 / 100μlE10-30052-AF750$485 / 100μlE10-30052-AF790$485 / 100μlE10-30052-APC$485 / 100μlE10-30052-PE$485 / 100μlE10-30052-Cy3$485 / 100μlE10-30052-Cy5$485 / 100μlE10-30052-Cy5.5$485 / 100μlE10-30052-Cy7$485 / 100μlE10-30052-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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