BackgroundCdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Product Information
Clone Number1F12
SpeciesMouse IgG1
Entrez Gene995
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200-1/1000,
ELISA: Propose dilution 1/10000.
Molecular Weight58kDa
All Names
AlternameCDC25; CDC25C
ImmunogenPurified recombinant fragment of human CDC25C expressed in E. Coli
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells