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Primary Antibodies
p44/42 MAPK (Erk1/2) Antibody
Human; Mouse
WB, IHC, FC, ELISA. Not yet tested in other applications.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundMitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. Upon stimulation, a sequential three-part protein kinase cascade is initiated, consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K), and a MAP kinase (MAPK). Multiple p44/42 MAP3Ks have been identified, including members of the Raf family as well as Mos and Tpl2/Cot.
Product Information
Clone Number3F8
SpeciesMouse IgG1
Entrez Gene5594
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
Molecular Weight42kDa
All Names
AlternameERK; p38; p40; p41; ERK2; ERT1; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; MAPK1
ImmunogenPurified recombinant fragment of human MAPK expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1: Western blot analysis using p44/42 MAPK mouse mAb against Jurkat (1), Hela (2), A431 (3) and NIH/3T3 (4) cell lysate. Figure 3: Flow and negative control
Immunohistochemical analysis of paraffin-embedded human Liver tissues mouse mAb.
cytometric analysis of Jurkat cells using p44/42 MAPK mAb (green) (purple).
Conjugated Antibody
This product is also available conjugated. Format: E10-30014-Conjugate. Price: $485 / Size: 100μl.
E10-30014-FITC$485 / 100μlE10-30014-Biotin$485 / 100μlE10-30014-HRP$485 / 100μlE10-30014-AP$485 / 100μlE10-30014-AF350$485 / 100μlE10-30014-AF405M$485 / 100μlE10-30014-AF488$485 / 100μlE10-30014-AF514$485 / 100μlE10-30014-AF532$485 / 100μlE10-30014-AF555$485 / 100μlE10-30014-AF568$485 / 100μlE10-30014-AF405S$485 / 100μlE10-30014-AF405L$485 / 100μlE10-30014-AF546$485 / 100μlE10-30014-AF594$485 / 100μlE10-30014-AF610$485 / 100μlE10-30014-AF635$485 / 100μlE10-30014-AF647$485 / 100μlE10-30014-AF680$485 / 100μlE10-30014-AF700$485 / 100μlE10-30014-AF750$485 / 100μlE10-30014-AF790$485 / 100μlE10-30014-APC$485 / 100μlE10-30014-PE$485 / 100μlE10-30014-Cy3$485 / 100μlE10-30014-Cy5$485 / 100μlE10-30014-Cy5.5$485 / 100μlE10-30014-Cy7$485 / 100μlE10-30014-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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