BackgroundDkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
Product Information
Clone Number4G7
SpeciesMouse IgG1
Entrez Gene27122
Recommended DilutionsWB: 1/500 - 1/2000, FC: 1/200-1/400,
ELISA: Propose dilution 1/10000.
Molecular Weight38kDa
All Names
AlternameRIG; REIC
ImmunogenPurified recombinant fragment of human MAP2K2 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells