BackgroundThe androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.
Product Information
Clone Number2H8
SpeciesMouse IgG1
Entrez Gene367
Recommended DilutionsWB: 1/500 - 1/2000, IHC: 1/200 - 1/1000,
ELISA: Propose dilution 1/10000.
Molecular Weight110kDa
All Names
AlternameNR3C4; KD; AIS; SMAX1; HUMARA; AR
ImmunogenPurified recombinant fragment of human AR expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃.
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells