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Primary Antibodies
cAMP Antibody
ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundCyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery
Product Information
Clone Number9H4C4
SpeciesMouse IgG1
Recommended DilutionsELISA: Propose dilution 1/10000.
All Names
AlternamecAMP
ImmunogencAMP, conjugated to KLH.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Conjugated Antibody
This product is also available conjugated. Format: E10-20194-Conjugate. Price: $485 / Size: 100μl.
E10-20194-FITC$485 / 100μlE10-20194-Biotin$485 / 100μlE10-20194-HRP$485 / 100μlE10-20194-AP$485 / 100μlE10-20194-AF350$485 / 100μlE10-20194-AF405M$485 / 100μlE10-20194-AF488$485 / 100μlE10-20194-AF514$485 / 100μlE10-20194-AF532$485 / 100μlE10-20194-AF555$485 / 100μlE10-20194-AF568$485 / 100μlE10-20194-AF405S$485 / 100μlE10-20194-AF405L$485 / 100μlE10-20194-AF546$485 / 100μlE10-20194-AF594$485 / 100μlE10-20194-AF610$485 / 100μlE10-20194-AF635$485 / 100μlE10-20194-AF647$485 / 100μlE10-20194-AF680$485 / 100μlE10-20194-AF700$485 / 100μlE10-20194-AF750$485 / 100μlE10-20194-AF790$485 / 100μlE10-20194-APC$485 / 100μlE10-20194-PE$485 / 100μlE10-20194-Cy3$485 / 100μlE10-20194-Cy5$485 / 100μlE10-20194-Cy5.5$485 / 100μlE10-20194-Cy7$485 / 100μlE10-20194-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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