BackgroundCD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
Product Information
Clone Number3E9D3C1G3
SpeciesMouse IgG
Entrez Gene931
Recommended DilutionsIHC:1/200 - 1/1000,IF: 1/200 - 1/1000,ELISA: Propose dilution 1/10000.
All Names
AlternameB1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1
ImmunogenSynthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells