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Primary Antibodies
TIP60 Antibody
Human
WB, IHC,ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundHTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A. canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome.
Product Information
Clone Number8C4C4
SpeciesMouse IgG2b
Entrez Gene10524
Molecular Weight60KDa
Recommended DilutionsWB.1/500 - 1/2000 ,IHC.1/200 - 1/1000,ELISA. Propose dilution 1/10000.
All Names
AlternameTIP60 (HTATIP)
ImmunogenPurified recombinant fragment of human TIP60 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1. Western blot analysis using Tip60 mouse (D), mAb against truncated Tip60 recombinant protein.
Figure 2. Immunohistochemical analysis of paraffin- embedded human liver carcinoma (A), recturn carcinoma normal medulla tissue (C) and normal interbrain tissues showing nuclear localization using Tip60 mouse mAb with DAB staining.
Conjugated Antibody
This product is also available conjugated. Format: E10-20141-Conjugate. Price: $485 / Size: 100μl.
E10-20141-FITC$485 / 100μlE10-20141-Biotin$485 / 100μlE10-20141-HRP$485 / 100μlE10-20141-AP$485 / 100μlE10-20141-AF350$485 / 100μlE10-20141-AF405M$485 / 100μlE10-20141-AF488$485 / 100μlE10-20141-AF514$485 / 100μlE10-20141-AF532$485 / 100μlE10-20141-AF555$485 / 100μlE10-20141-AF568$485 / 100μlE10-20141-AF405S$485 / 100μlE10-20141-AF405L$485 / 100μlE10-20141-AF546$485 / 100μlE10-20141-AF594$485 / 100μlE10-20141-AF610$485 / 100μlE10-20141-AF635$485 / 100μlE10-20141-AF647$485 / 100μlE10-20141-AF680$485 / 100μlE10-20141-AF700$485 / 100μlE10-20141-AF750$485 / 100μlE10-20141-AF790$485 / 100μlE10-20141-APC$485 / 100μlE10-20141-PE$485 / 100μlE10-20141-Cy3$485 / 100μlE10-20141-Cy5$485 / 100μlE10-20141-Cy5.5$485 / 100μlE10-20141-Cy7$485 / 100μlE10-20141-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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