World supplier of antibodies, antigens and kits since 2007
Primary Antibodies
IGF1R Antibody
Human
WB, IHC,ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
$225/ 100μg/100μl
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
BackgroundIGF1R (insulin-like growth factor 1 receptor), a transmembrane receptor tyrosine kinase, is widely expressed in many cell types within fetal and postnatal tissues, and in many cell lines. Upon binding to its ligands, IGF-I and IGF-II, receptor autophosphorylation occurs. The triple tyrosine cluster within the kinase domain (Tyr1131, Tyr1135 and Tyr1136) is the earliest major site of autophosphorylation. Phosphorylation of these three tyrosine residues is necessary for kinase activation.Insulin receptors (IRs) share significant similarity with IGF1 receptors in both structure and function,including an equivalent triple tyrosine cluster within the activation loop of the kinase domain (Tyr1146, Tyr1150 and Tyr1151).Tyrosine autophosphorylation of insulin receptor is one of the earliest cellular responses to insulin stimulation. Autophosphorylation begins with phosphorylation of Tyr1146 and either Tyr1150 or Tyr1151. Full kinase activation requires the triple tyrosine phosphorylation.
Product Information
Clone Number3C8B1
SpeciesMouse IgG2b
Entrez Gene3480
Recommended DilutionsWB.1/500 - 1/2000 ,IHC .1/200 - 1/1000,ELISA. Propose dilution 1/10000.
All Names
AlternameIGF1R
ImmunogenPurified recombinant fragment of IGF1R expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃
Form Or Antibody
Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1. Western blot analysis using IGF1R carcinoma(uterus)(C), mouse mAb against truncated IGF1R carcinoma(E), recombinant protein. localization using
Immunohistochemical analysis of paraffin-embedded human adenocarcinoma(A), colon adenocarcinoma(B), endometrial ovary adenocarcinoma(D), lung squamous cell stomach epithelium mucosae(F), showing membrane IGF1R mouse mAb with DAB staining.
Conjugated Antibody
This product is also available conjugated. Format: E10-20138-Conjugate. Price: $485 / Size: 100μl.
E10-20138-FITC$485 / 100μlE10-20138-Biotin$485 / 100μlE10-20138-HRP$485 / 100μlE10-20138-AP$485 / 100μlE10-20138-AF350$485 / 100μlE10-20138-AF405M$485 / 100μlE10-20138-AF488$485 / 100μlE10-20138-AF514$485 / 100μlE10-20138-AF532$485 / 100μlE10-20138-AF555$485 / 100μlE10-20138-AF568$485 / 100μlE10-20138-AF405S$485 / 100μlE10-20138-AF405L$485 / 100μlE10-20138-AF546$485 / 100μlE10-20138-AF594$485 / 100μlE10-20138-AF610$485 / 100μlE10-20138-AF635$485 / 100μlE10-20138-AF647$485 / 100μlE10-20138-AF680$485 / 100μlE10-20138-AF700$485 / 100μlE10-20138-AF750$485 / 100μlE10-20138-AF790$485 / 100μlE10-20138-APC$485 / 100μlE10-20138-PE$485 / 100μlE10-20138-Cy3$485 / 100μlE10-20138-Cy5$485 / 100μlE10-20138-Cy5.5$485 / 100μlE10-20138-Cy7$485 / 100μlE10-20138-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Primary Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- ELISA Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits
- Overexpression Cell Lines
- Cell Lysates
- Purification Resins
- 2019-nCoV & Monkeypox