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Primary Antibodies

GSK3 alpha Antibody

E10-20134Cite ID: EN0013395DatasheetCOAMSDS
Human
WB, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
$225/ 100μg/100μl
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

BackgroundGlycogen synthase kinase 3 alpha belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, myb, and the transcription factor c jun. GSK3 phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK3 and subsequently inhibits GSK3 acutely leading to the stimulation of glycogen synthesis. GSK3 signaling is performed by two isoforms, GSK3 alpha and GSK3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

Product Information

Clone Number6G12C2
SpeciesMouse IgG1
Entrez Gene2931
Recommended DilutionsWB:1/500 - 1/2000 ,ELISA: Propose dilution 1/10000.

All Names

AlternameDKFZp686D0638; GSK3A
ImmunogenPurified recombinant fragment of GSK3 alpha expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃

Form Or Antibody

Form of AntibodyAscitic fluid containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
1: Western blot analysis using GSK3 alpha mouse mAb against protein (1)and Hela cell lysate (2) .
1: Western blot analysis using GSK3 alpha mouse mAb against protein (1)and Hela cell lysate (2) .

Conjugated Antibody

This product is also available conjugated. Format: E10-20134-Conjugate. Price: $485 / Size: 100μl.

E10-20134-FITC$485 / 100μlE10-20134-Biotin$485 / 100μlE10-20134-HRP$485 / 100μlE10-20134-AP$485 / 100μlE10-20134-AF350$485 / 100μlE10-20134-AF405M$485 / 100μlE10-20134-AF488$485 / 100μlE10-20134-AF514$485 / 100μlE10-20134-AF532$485 / 100μlE10-20134-AF555$485 / 100μlE10-20134-AF568$485 / 100μlE10-20134-AF405S$485 / 100μlE10-20134-AF405L$485 / 100μlE10-20134-AF546$485 / 100μlE10-20134-AF594$485 / 100μlE10-20134-AF610$485 / 100μlE10-20134-AF635$485 / 100μlE10-20134-AF647$485 / 100μlE10-20134-AF680$485 / 100μlE10-20134-AF700$485 / 100μlE10-20134-AF750$485 / 100μlE10-20134-AF790$485 / 100μlE10-20134-APC$485 / 100μlE10-20134-PE$485 / 100μlE10-20134-Cy3$485 / 100μlE10-20134-Cy5$485 / 100μlE10-20134-Cy5.5$485 / 100μlE10-20134-Cy7$485 / 100μlE10-20134-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.