BackgroundInterleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
Product Information
Clone Number1F3B3,3A6F11
SpeciesMouse IgG2a
Entrez Gene3552
Recommended DilutionsWB.1/500 - 1/2000, ELISA. Propose dilution 1/10000.
All Names
AlternameIL1; IL-1A; IL1F1; IL1-ALPHA
ImmunogenPurified recombinant fragment of human IL1a expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃
Form Or Antibody
Form of AntibodyPurified antibody in PBS containing 0.03% sodium azide.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells