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Primary Antibodies

BCL-10 Antibody

E10-20003Cite ID: EN0013279DatasheetCOAMSDS
Human; Mouse
WB, IHC,IF, FCM, ELISA. Not yet tested in other applications. Determining optimal working dilutions by titration test.
$225/ 100μg/100μl
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

BackgroundBcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.

Product Information

Clone Number4F8
SpeciesMouse IgG1
Entrez Gene8915
Recommended DilutionsWB.1/500 - 1/2000, IHC.1/200 - 1/1000, IF.1/200 - 1/1000, FCM.1/200 - 1/400 ELISA. Propose dilution 1/10000.
Molecular Weight26kDa

All Names

AlternameCLAP; Me10; CIPER; c-E10; CARMEN
ImmunogenPurified recombinant fragment of human BCL-10 expressed in E. Coli.
Storage/StabilityStore at 4℃, for long term storage, store at -20℃

Form Or Antibody

Form of AntibodyPurified antibody in PBS containing 0.03% sodium azide.
Price225$
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
Figure 1. Western blot analysis using BCL10 mouse mAb against NIH/3T3 (1), Hela (2), MCF-7 (3) and Jurka Figure 3.Confocal (4) cell lysate (right) cells labeled with
Figure 1. Western blot analysis using BCL10 mouse mAb against NIH/3T3 (1), Hela (2), MCF-7 (3) and Jurka Figure 3.Confocal (4) cell lysate (right) cells labeled with
Figure 2. Immunohistochemical analysis ofparaffin-embedded human breast carcinoma (A) and liver carcinoma (B), showing cytoplasmic localization using BCL10mouse mAb with DAB staining.
Figure 2. Immunohistochemical analysis ofparaffin-embedded human breast carcinoma (A) and liver carcinoma (B), showing cytoplasmic localization using BCL10mouse mAb with DAB staining.
immunofluorescence analysis of Hela (left) and NTERA-2 using NPM mouse mAb (green). Red: Actin filaments have been DY-554 phalloidin.
immunofluorescence analysis of Hela (left) and NTERA-2 using NPM mouse mAb (green). Red: Actin filaments have been DY-554 phalloidin.

Conjugated Antibody

This product is also available conjugated. Format: E10-20003-Conjugate. Price: $485 / Size: 100μl.

E10-20003-FITC$485 / 100μlE10-20003-Biotin$485 / 100μlE10-20003-HRP$485 / 100μlE10-20003-AP$485 / 100μlE10-20003-AF350$485 / 100μlE10-20003-AF405M$485 / 100μlE10-20003-AF488$485 / 100μlE10-20003-AF514$485 / 100μlE10-20003-AF532$485 / 100μlE10-20003-AF555$485 / 100μlE10-20003-AF568$485 / 100μlE10-20003-AF405S$485 / 100μlE10-20003-AF405L$485 / 100μlE10-20003-AF546$485 / 100μlE10-20003-AF594$485 / 100μlE10-20003-AF610$485 / 100μlE10-20003-AF635$485 / 100μlE10-20003-AF647$485 / 100μlE10-20003-AF680$485 / 100μlE10-20003-AF700$485 / 100μlE10-20003-AF750$485 / 100μlE10-20003-AF790$485 / 100μlE10-20003-APC$485 / 100μlE10-20003-PE$485 / 100μlE10-20003-Cy3$485 / 100μlE10-20003-Cy5$485 / 100μlE10-20003-Cy5.5$485 / 100μlE10-20003-Cy7$485 / 100μlE10-20003-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.