Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human CHK2 around the phosphorylation site of threonine 387.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityCHK2 (Ab-387) antibody detects endogenous levels of total CHK2 protein.
ReferencesGabant G, et al. (2008) J Mol Biol 380, 489-503.
Gupta SK, et al. (2007) J Biol Chem 282, 29431-40.
Oliva-Trastoy M, et al. (2007) Oncogene 26, 1449-58.
Kastan, M.B. and Lim, D.S. (2000) Nat. Rev. Mol. Cell Biol. 1, 179-186.
Matsuoka, S. et al. (2000) Proc. Natl. Acad. Sci. USA 97, 10389-10394.
Melchionna, R. et al. (2000) Nat. Cell Biol. 2, 762-765.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells