Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human CHK1 around the phosphorylation site of serine 317.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityCHK1 (Ab-317) antibody detects endogenous levels of total CHK1 protein.
ReferencesDephoure N, et al. (2008) Proc Natl Acad Sci U S A 105, 10762-7.
Cruet-Hennequart S, et al. (2008) DNA Repair (Amst) 7, 582-96.
Matsuoka S, et al. (2007) Science 316, 1160-6.
Carlessi L, et al. (2007) Mol Cancer Ther 6, 935-44.
Stiff T, et al. (2006) EMBO J 25, 5775-82.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells