Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1423 (H-G-SP-Q-P).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityBRCA1 (Ab-1423) antibody detects endogenous levels of total BRCA1 protein.
ReferencesKim ST, et al. (2002) Genes Dev; 16(5): 560-570
Arlt MF, et al. (2004) Mol Cell Biol; 24(15): 6701-6709
Zhang J, et al. (2004) Mol Cell Biol; 24(2): 708-718
Greenberg RA, et al. (2006) Genes Dev; 20(1): 34-46
Tibbetts RS, et al. (2000) Genes Dev; 14(23): 2989-3002
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells