Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human 4E-BP1 around the phosphorylation site of threonine 36 (S-T-TP-P-G).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/Sensitivity4E-BP1 (Ab-36) antibody detects endogenous levels of total 4E-BP1 protein. This antibody may cross-react with 4E-BP2 and 4E-BP3.
ReferencesGingras AC, et al. Genes Dev Nov. 2005 Feb 15.
Mothe-Satney I, et al.(2000) J Biol Chem:15(21): 2852-64.
Gingras AC, et al. (1999) Genes Dev:13(11): 1422-37.
Lal L, et al.(2005) Blood;105(4): 1669-7.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells