Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human PDGFR beta around the phosphorylation site of tyrosine 751 (V-D-YP-V-P).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityPDGFR beta (phospho-Tyr751) antibody detects endogenous levels of PDGFR beta only when phosphorylated at tyrosine 751.
ReferencesBergsten, E. et al. (2001) Nat. Cell Biol. 3, 512-516
Kovalenko M, et al. (2000) J Biol Chem 275, 16219-26
Ramalingam, K. et al. (1995) Bioorg. Med. Chem. 3, 1263-1272
Wennström S, et al. (1994) Oncogene 9, 651-60
Kazlauskas A, Kashishian A, Cooper JA, Valius M (1992) Mol Cell Biol 12, 2534-44
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells